DPSCREEN: Dynamic Personalized Screening

نویسندگان

  • Kartik Ahuja
  • William R. Zame
  • Mihaela van der Schaar
چکیده

Screening in Operations Research and Statistics • Partially Observable Markov Decision Process POMDP (Ayer et.al.) • Bayesian Optimal Design (Rizopoulos et.al.) • Pros: Principled search for optimal policies • Cons: Markov/Semi-Markov, Stationary Screening in Medical Literature • Stochastic simulation based (Frazie et.al. ) • Pros: No assumptions on disease models • Cons: Not personalized, Compare a fixed set of policies chosen by experts This work No assumptions on disease models! Principled search for optimal policies! MODEL AND PROBLEM FORMULATION

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Diet-Microbiota Interactions: A New Approach to Personalized Nutrition

 Personalized nutrition is a new approach in medical sciences that is based on genetic profile, individual needs, and environmental conditions considering health status and chronic diseases of every person. Studies have shown that genetic differences cannot solely justify various responses to medications and diets, and other important factors including gut microbiota are also involved. Human bo...

متن کامل

Personalized drug discovery: HCA approach optimized for rare diseases at Tel Aviv University.

The Cell screening facility for personalized medicine (CSFPM) at Tel Aviv University in Israel is devoted to screening small molecules libraries for finding new drugs for rare diseases using human cell based models. The main strategy of the facility is based on smartly reducing the size of the compounds collection in similarity clusters and at the same time keeping high diversity of pharmacopho...

متن کامل

The impact of personalized risk communication on screening decisions.

Practice Pointers Screening tests are not appropriate for every patient. Instead, individual risk and personal values play a role in determining whether a given patient should undergo screening for a disease. Many guidelines recommend that physicians have a discussion with patients when determining whether to perform a specific screening test, and many guidelines use individual risk as a differ...

متن کامل

Public health genomics and personalized prevention: lessons from the COGS project

Using the principles of public health genomics, we examined the opportunities and challenges of implementing personalized prevention programmes for cancer at the population level. Our model-based estimates indicate that polygenic risk stratification can potentially improve the effectiveness and cost-effectiveness of screening programmes. However, compared with 'one-size-fits-all' screening prog...

متن کامل

Developing an assessment-centered e-Learning system for improving student learning effectiveness

This research used Web-based two-tier diagnostic assessment and Web-based dynamic assessment to develop an assessment-centered e-Learning system, named the ‘GPAM-WATA e-Learning system.’ This system consists of two major designs: (1) personalized dynamic assessment, meaning that the system automatically generates dynamic assessment for each learner based on the results of the pre-test of the tw...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017